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TIPRL Polyclonal Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A) . Isoform 1 inhibits catalytic activity of the PP2A (D) core complex in vitro. The PP2A (C) :TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair.

Synonyms

TIP41-like protein; TIPRL; Putative MAPK-activating protein PM10; Type 2A-interacting protein; TIP

Gene ID

26172

Swiss Prot

O75663

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

51-150/272

Target

TIPRL

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 405

Source

KLH conjugated synthetic peptide derived from human TIPRL

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

26172

Predicted Cross Reactivity

Human, Rat, Dog, Cow, Pig, Horse, Rabbit, GuineaPig

Curated Selection

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