GRM4 Polyclonal Antibody, PE Conjugated

Product Specifications

Background

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.

Synonyms

MGlu4; GPRC1D; MGLUR4; Metabotropic glutamate receptor 4; GRM4

Gene ID

2914

Swiss Prot

Q14833

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

301-400/912

Target

GRM4

Clonality

Polyclonal

Isotype

IgG

Conjugation

Source

KLH conjugated synthetic peptide derived from human Metabotropic Glutamate Receptor 4

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This antibody detects Metabotropic Glutamate Receptor 4. It may also detect Metabotropic Glutamate Receptor 6 due to sequence similarity.

Gene ID URL

2914

Predicted Cross Reactivity

Human, Pig, Rabbit

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