Rad52 Polyclonal Antibody

DNA double-strand breaks can be generated by exposure to ionizing radiation or through endogenous cellular reactions. Double-strand breaks are generally thought to be repaired via one of two distinct mechanisms: homologous recombination (HR) or non-homologous end joining (NHEJ) . Homologous recombination requires the activity of the members of the RAD52 epistasis group, which include RAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2. RAD52 can catalyze strand annealing reactions, and can form oligomers that attach to ends of single-stranded DNA.

DNA repair protein RAD52; DNA repair protein RAD52 homolog; RAD 52; RAD52 homolog S. cerevisiae; RAD52 homolog; Recombination protein RAD52; Rhabdomyosarcoma antigen MU RMS 40.23.