Profilin 2 Polyclonal Antibody, Cy3 Conjugated
Product Specifications
Background
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity) .
Synonyms
Profilin-2; Profilin II; Pfn2
Gene ID
81531
Swiss Prot
Q9EPC6
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Immunogen
51-140/140
Target
Profilin 2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy3
Source
KLH conjugated synthetic peptide derived from rat Profilin 2
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
512,550nm/570,615nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
This antibody may detect Profilin 1 due to a 71% amino acid sequence similarity in the immunogen sequence.
Gene ID URL
81531
Predicted Cross Reactivity
Mouse, Rat, Cow, Pig, Chicken
Curated Selection
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