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Profilin 2 Polyclonal Antibody

Product Specifications

Background

Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity) .

Synonyms

Profilin-2; Profilin II; Pfn2

Gene ID

81531

Swiss Prot

Q9EPC6

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Immunogen

51-140/140

Target

Profilin 2

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from rat Profilin 2

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Specificity

This antibody may detect Profilin 1 due to a 71% amino acid sequence similarity in the immunogen sequence.

Gene ID URL

81531

Predicted Cross Reactivity

Mouse, Rat, Cow, Pig, Chicken

Curated Selection

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