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MDFI Polyclonal Antibody, AbBy Fluor™ 680 Conjugated

Product Specifications

Background

Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways (By similarity) .

Synonyms

I MF; I mfa; Inhibitor of MyoD family a; Mdfi; MDFI_HUMAN; MyoD family inhibitor; Myogenic repressor I-mf; OTTHUMP00000016375; OTTHUMP00000016376; OTTHUMP00000196103; OTTHUMP00000196414; OTTHUMP00000196415.

Gene ID

4188

Swiss Prot

Q99750

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human

Immunogen

101-200/246

Target

MDFI

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 680

Source

KLH conjugated synthetic peptide derived from human MDFI

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

679nm/702nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-18743R-BF680

Specificity

In Mice, there is possible cross-reactivity with Glycoprotein endo-alpha-1,2-mannosidase (67% homology with immunogen sequence; 53kDa)

Gene ID URL

4188

Predicted Cross Reactivity

Mouse, Rat, Cow, Sheep, Pig, Horse

Curated Selection

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