MCM-BP Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion.
Synonyms
C10orf119 ; chromosome 10 open reading frame 119 ; MCM-binding protein ; MCM-BP ; mcmbp ; MCMBP_HUMAN ; Mini-chromosome maintenance complex-binding protein ; Minichromosome maintenance complex binding protein.
Gene ID
79892
Swiss Prot
Q9BTE3
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Rat
Immunogen
551-642/642
Target
MCM-BP
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human MCM-BP
Applications
IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
79892
Predicted Cross Reactivity
Human, Mouse, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2613445-01 48 Well
Mouse cutA divalent cation tolerance homolog (E. coli) (CUTA) ELISA Kit
Ask
View Details MBS2613445-02 96 Well
Mouse cutA divalent cation tolerance homolog (E. coli) (CUTA) ELISA Kit
Ask
View Details 
MBS2613445-03 5x 96 Well
Mouse cutA divalent cation tolerance homolog (E. coli) (CUTA) ELISA Kit
Ask
View Details MBS2613445-04 10x 96 Well
Mouse cutA divalent cation tolerance homolog (E. coli) (CUTA) ELISA Kit
Ask
View Details 