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MCM-BP Polyclonal Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion.

Synonyms

C10orf119 ; chromosome 10 open reading frame 119 ; MCM-binding protein ; MCM-BP ; mcmbp ; MCMBP_HUMAN ; Mini-chromosome maintenance complex-binding protein ; Minichromosome maintenance complex binding protein.

Gene ID

79892

Swiss Prot

Q9BTE3

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Rat

Immunogen

551-642/642

Target

MCM-BP

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic peptide derived from human MCM-BP

Applications

IF

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

1µg/µl

Dilution

IF (IF=1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

79892

Predicted Cross Reactivity

Human, Mouse, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit

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