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HIF Prolyl Hydroxylases Polyclonal Antibody, Cy5.5 Conjugated

Product Specifications

Background

The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

Synonyms

Transmembrane prolyl 4-hydroxylase; Proline hydrolase 4; proline 4-hydroxylase; P4htm; hypoxia-inducible factor prolyl 4-hydroxylase; P4H-TM; H-prolyl hydroxylase PH-4; P4HTM_HUMAN; Hypoxia-inducible factor prolyl hydroxylase 4; H-PH4; H-prolyl hydroxylase 4; HPH-4; transmembrane prolyl 4-hydroxylase isoform a; P4HTM; EGLN4; HPH4; P4H-TM; PH-4; PH4; PHD4; P4H with transmembrane domain; Prolyl hydroxlase domain-containing 4; hypoxia inducible factor prolyl 4 hydroxylase; H-prolyl hydroxylase 4.

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

201-300/502

Target

HIF Prolyl Hydroxylases

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy5.5

Source

KLH conjugated synthetic peptide derived from human PH-4

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

675nm/694nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Predicted Cross Reactivity

Human, Dog, Cow, Pig, Horse, Rabbit

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