HIF Prolyl Hydroxylases Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Synonyms
Transmembrane prolyl 4-hydroxylase; Proline hydrolase 4; proline 4-hydroxylase; P4htm; hypoxia-inducible factor prolyl 4-hydroxylase; P4H-TM; H-prolyl hydroxylase PH-4; P4HTM_HUMAN; Hypoxia-inducible factor prolyl hydroxylase 4; H-PH4; H-prolyl hydroxylase 4; HPH-4; transmembrane prolyl 4-hydroxylase isoform a; P4HTM; EGLN4; HPH4; P4H-TM; PH-4; PH4; PHD4; P4H with transmembrane domain; Prolyl hydroxlase domain-containing 4; hypoxia inducible factor prolyl 4 hydroxylase; H-prolyl hydroxylase 4.
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
201-300/502
Target
HIF Prolyl Hydroxylases
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic peptide derived from human PH-4
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Predicted Cross Reactivity
Human, Dog, Cow, Pig, Horse, Rabbit
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