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SPDEF Polyclonal Antibody, PE-Cy7 Conjugated

Product Specifications

Background

SPDEF, also known as PDEF is an ETS transcription factor expressed in the prostate epithelial cells. It is thought to act as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter and also as a transcriptional activator for the SERPINB5 promoter. It is highly expressed in prostate carcinoma cells and is thought to be involved in the regulation of the prostate gland and/or prostate cancer development. It is also expressed in epithelial breast carcinoma.

Synonyms

BA375E1.3; PDEF; Prostate derived Ets factor; PROSTATE EPITHELIUM SPECIC ETS TRANSCRIPTION FACTOR; Prostate epithelium-specic Ets transcription factor; Prostate specic Ets; Prostate-derived Ets factor; Prostate-specic Ets; PSE; RP11-375E1__A.3; SAM POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR; SAM pointed domain-containing Ets transcription factor; Spdef; SPDEF_HUMAN.

Gene ID

25803

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

251-335/335

Target

SPDEF

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy7

Source

KLH conjugated synthetic peptide derived from human PDEF

Applications

FCM

Purification

Purified by Protein A.

Excitation Emission

488nm/780nm

Concentration

1µg/µl

Dilution

FCM (1:20-100)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

25803

Predicted Cross Reactivity

Dog, Cow, Horse, Chicken, Rabbit

Curated Selection

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