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PAX5 Polyclonal Antibody, RBITC Conjugated

Product Specifications

Background

The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.

Synonyms

B cell lineage specic activator; B cell lineage specic activator protein; B cell specic activator protein; B cell specic transcription factor; B-cell-specic transcription factor; BSAP; EBB-1; KLP; Paired box 5; Paired box gene 5 B cell lineage specic activator protein; Paired box gene 5 B cell lineage specic activator; Paired box gene 5; Paired box homeotic gene 5; Paired box protein Pax 5; Paired box protein Pax-5; Paired domain gene 5; PAX 5; PAX5; PAX5_HUMAN; Transcription factor PAX 5.

Gene ID

5079

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Immunogen

301-391/391

Target

PAX5

Clonality

Polyclonal

Isotype

IgG

Conjugation

RBITC

Source

KLH conjugated synthetic peptide derived from human PAX5

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5079

Predicted Cross Reactivity

Mouse, Rat, Cow, Pig, Chicken

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