MMP16 Polyclonal Antibody, PE Conjugated
Product Specifications
Background
Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
Synonyms
MMP-X2; C8orf57; MT-MMP2; MT-MMP3; MT3-MMP; Matrix metalloproteinase-16; MMP-16; Membrane-type matrix metalloproteinase 3; MT-MMP 3; MTMMP3; Membrane-type-3 matrix metalloproteinase; MT3MMP; MMP16; MMPX2
Gene ID
4325
Swiss Prot
P51512
Cellular Locus
Cell membrane, Extracellular matrix
Host
Rabbit
Immunogen
501-607/607
Target
MMP16
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human MMP-16
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
4325
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit
Available Sizes
Curated Selection
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