MMP15 Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. [provided by RefSeq, Jul 2008].
Synonyms
Matrix metalloproteinase-15; MMP 15; MMP15; Matrix metallopeptidase 15 membrane inserted; Matrix metalloproteinase 15 ; Membrane type 2 Matrix Metalloproteinase; Membrane type matrix metalloproteinase 2; MMP 15; MT MMP 2; MT2 MMP; MT2MMP; MTMMP 2; MTMMP2; SMCP 2; SMCP2; MMP15_HUMAN.
Gene ID
4324
Cellular Locus
Cell membrane, Extracellular matrix
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
501-600/669
Target
MMP15
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human MMP15
Applications
WB, ELISA
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
4324
Predicted Cross Reactivity
Human, Rat, Dog, Cow, Pig, Horse
Curated Selection
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