Pomalidomide-CO-C5-Br

Pomalidomide-CO-C5-Br (Compound 6b) is a conjugated compound of the E3 ligand Pomalidomide and linker. It can be used to synthesize highly effective PROTAC molecules targeting ADC (HY-169008) [1].

Product Specifications

CAS Number

[2227423-38-1]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/pomalidomide-co-c5-br.html

Smiles

O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NC(CCCCCBr)=O)=CC=C3)=O)=O

Molecular Formula

C19H20BrN3O5

Molecular Weight

450.28

References & Citations

[1]Xu Q, et al. Acetyl-CoA Carboxylase Proteolysis-Targeting Chimeras: Conceptual Design and Application as Insecticides. J Agric Food Chem. 2024 Aug 28;72 (34) :18809-18815.