KCNA5 Polyclonal Antibody, APC-Cy7 Conjugated

Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. This channel displays rapid activation and slow inactivation. May play a role in regulating the secretion of insulin in normal pancreatic islets. Isoform 2 exhibits a voltage-dependent recovery from inactivation and an excessive cumulative inactivation.

HK2; HCK1; PCN1; ATFB7; HPCN1; KV1.5; Potassium voltage-gated channel subfamily A member 5; Voltage-gated potassium channel HK2; Voltage-gated potassium channel subunit Kv1.5; KCNA5