PPARGC1A Polyclonal Antibody, FITC Conjugated
Product Specifications
Background
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs) . It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity (referenced from entrez gene.
Synonyms
LEM6; PGC-1 Alpha; PGC1 Alpha; Ligand effect modulator 6; Peroxisome prolerative activated receptor, gamma, coactivator 1 alpha; Peroxisome prolerative activated receptor, gamma, coactivator 1 ; Peroxisome prolerator activated receptor gamma coactivator 1 alpha; PGC 1 alpha; PGC 1 alpha; PGC 1v; PGC1; PGC1alpha; PGC1A; PGC1v; PPAR gamma coactivator 1 alpha 3 ligand effect modulator 6; PPAR gamma coactivator 1 alpha; PPAR gamma coactivator 1; PPAR gamma coactivator variant form; PPARGC 1 alpha; PPARGC1A.
Gene ID
10891
Swiss Prot
Q9UBK2
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Immunogen
601-700/798
Target
PPARGC1A
Clonality
Polyclonal
Isotype
IgG
Conjugation
FITC
Source
KLH conjugated synthetic peptide derived from human PPARGC1A
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
494nm/518nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.biossantibodies.com/datasheets/bs-1832R-FITC
Specificity
76% homology with PGC1 beta
Gene ID URL
10891
Predicted Cross Reactivity
Mouse, Rat
Curated Selection
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