LGI2 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LGI2 (leucine-rich repeat LGI family, member 2), also known as KIAA1916 or LGIL2, is a 545 amino acid secreted protein that contains four LRR repeats and seven EAR repeats. Expressed in heart, brain and placenta, LGI2 shares high sequence similarity with other LGI family members and is thought to play a role in the pathogenesis of epileptic disorders.
Synonyms
KIAA1916; Leucine rich glioma inactivated protein 2; Leucine rich repeat LGI family member 2; Leucine-rich glioma-inactivated protein 2; Leucine-rich repeat LGI family member 2; LGI1 like protein 2; LGI1-like protein 2; LGI2; LGI2_HUMAN; LGIL2.
Gene ID
55203
Swiss Prot
Q8N0V4
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
201-300/545
Target
LGI2
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human LGI2
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
55203
Predicted Cross Reactivity
Human, Rat, Cow, Sheep, Pig, Horse, Chicken, GuineaPig
Curated Selection
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