ERG/KCNH2 Polyclonal Antibody, Biotin Conjugated

Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) . Isoforms USO have no channel activity by themself, but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation.

ERG1; HERG; LQT2; SQT1; ERG-1; H-ERG; HERG1; Kv11.1; Potassium voltage-gated channel subfamily H member 2; Eag homolog; Ether-a-go-go-related gene potassium channel 1; Eag-related protein 1; Ether-a-go-go-related protein 1; hERG-1; Voltage-gated potassium channel subunit Kv11.1; KCNH2; ERG