ERG/KCNH2 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) . Isoforms USO have no channel activity by themself, but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation.
Synonyms
ERG1; HERG; LQT2; SQT1; ERG-1; H-ERG; HERG1; Kv11.1; Potassium voltage-gated channel subfamily H member 2; Eag homolog; Ether-a-go-go-related gene potassium channel 1; Eag-related protein 1; Ether-a-go-go-related protein 1; hERG-1; Voltage-gated potassium channel subunit Kv11.1; KCNH2; ERG
Gene ID
3757
Swiss Prot
Q12809
Cellular Locus
Cell membrane
Host
Rabbit
Immunogen
1001-1159/1159
Target
ERG/KCNH2
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human HERG
Applications
FCM
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
FCM (1:20-100)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3757
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Pig, Horse, Rabbit
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