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ERG/KCNH2 Polyclonal Antibody

Product Specifications

Background

Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) . Isoforms USO have no channel activity by themself, but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation.

Synonyms

ERG1; HERG; LQT2; SQT1; ERG-1; H-ERG; HERG1; Kv11.1; Potassium voltage-gated channel subfamily H member 2; Eag homolog; Ether-a-go-go-related gene potassium channel 1; Eag-related protein 1; Ether-a-go-go-related protein 1; hERG-1; Voltage-gated potassium channel subunit Kv11.1; KCNH2; ERG

Gene ID

3757

Swiss Prot

Q12809

Cellular Locus

Cell membrane

Host

Rabbit

Immunogen

1001-1159/1159

Target

ERG/KCNH2

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human HERG

Applications

ELISA, FCM

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), FCM (1:20-100)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

3757

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Pig, Horse, Rabbit

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