GATA4 Polyclonal Antibody, APC-Cy7 Conjugated

Product Specifications

Background

Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP) -mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.

Synonyms

TOF; ASD2; VSD1; TACHD; Transcription factor GATA-4; GATA-binding factor 4; GATA4

Gene ID

2626

Swiss Prot

P43694

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

261-360/442

Target

GATA4

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated synthetic peptide derived from human GATA-4

Applications

WB, IF (IHC-P), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

May also interact with GATA-5, GATA-6

Gene ID URL

2626

Predicted Cross Reactivity

Human, Rat, Dog, Cow, Pig, Chicken, Rabbit

Curated Selection

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