OXR1 Polyclonal Antibody
Product Specifications
Background
Reactive oxygen species (ROS) are highly reactive molecules that are a normal consequence of aerobic metabolism. Cellular ROS damage can induce apoptosis and spontaneous mutagenesis. Oxr1 (Oxidation resistance protein 1) is a 758 amino acid mitochondrial protein that is most likely involved in protection from oxidative damage. Oxr1 is highly conserved from yeast to humans and is specific to eukaryotes.Induced by heat and oxidative stress, the carboxyl-terminal half of Oxr1 is required for its function. Upregulation of superoxide dismutase and catalase was observed in developing drosophila mutants that lacked the gene encoding Oxr1, suggesting that oxidative stress may trigger compensatory protein expression. There are four isoforms of Oxr1 that are produced as a result of alternative splicing events.
Synonyms
C7; C7B; Gm1238; Nbla00307; Nucleolar protein C7; Oxidation resistance 1; Oxidation resistance protein 1; Oxr1; OXR1_HUMAN; Putative protein product of Nbla00307; rCG_59825.
Gene ID
55074
Swiss Prot
Q8N573
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
31-130/874
Target
OXR1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human OXR1
Applications
WB, IHC-P, IHC-F, IF
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (WB=1:500-2000), IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500), IF (IF=1:100-500)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
55074
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