OTUD5/DUBA Polyclonal Antibody, PE Conjugated
Product Specifications
Background
Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro) .
Synonyms
DUBA; OTU domain-containing protein 5; Deubiquitinating enzyme A; OTUD5
Gene ID
55593
Swiss Prot
Q96G74
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Immunogen
501-571/571
Target
OTUD5/DUBA
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human OTUD5
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
55593
Predicted Cross Reactivity
Mouse, Rat, Chicken, Rabbit
Curated Selection
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