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OTUD5/DUBA Polyclonal Antibody, Cy3 Conjugated

Product Specifications

Background

Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro) .

Synonyms

DUBA; OTU domain-containing protein 5; Deubiquitinating enzyme A; OTUD5

Gene ID

55593

Swiss Prot

Q96G74

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Immunogen

501-571/571

Target

OTUD5/DUBA

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human OTUD5

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

55593

Predicted Cross Reactivity

Mouse, Rat, Chicken, Rabbit

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