RNF109/TRIM56 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN-beta following detection of pathogen- and host-derived double-stranded DNA (By similarity) .
Synonyms
A130009K11Rik; DKFZp667O116; E3 ubiquitin-protein ligase TRIM56; FLJ35608; Gm452; MGC37358; OTTMUSP00000027392; RING finger protein 109; RNF109; TRI56_HUMAN; Trim56; Tripartite motif containing protein 56; Tripartite motif-containing protein 56.
Gene ID
81844
Swiss Prot
Q9BRZ2
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Rat
Immunogen
651-755/755
Target
RNF109/TRIM56
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human RNF109/TRIM56
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
81844
Predicted Cross Reactivity
Human, Mouse, Dog, Cow, Sheep, Horse, Rabbit
Curated Selection
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