Desoxypeganine (hydrochloride)

Desoxypeganine (Deoxypeganine) hydrochloride, an alkaloid, is a potent and orally active cholinesterase (BChE and AChE) and selective MAO-A inhibitor, with IC50 values of 2, 17, and 2 μM, respectively. Desoxypeganine hydrochloride can be used for alcohol abuse research[1].

Product Specifications

CAS Number

[61939-05-7]

Product Name Alternative

Deoxypeganine (hydrochloride) ; Deoxyvasicine (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Cholinesterase (ChE) ; Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/desoxypeganine-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

[H]Cl.C12=NC3=C(C=CC=C3)CN1CCC2

Molecular Formula

C11H13ClN2

Molecular Weight

208.69

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

References & Citations

[1]Zheng XY, et al. Acetylcholinesterase inhibitive activity-guided isolation of two new alkaloids from seeds of Peganum nigellastrum Bunge by an in vitro TLC- bioautographic assay. Arch Pharm Res. 2009 Sep;32 (9) :1245-51. |[2]Doetkotte R, et al. Reduction of voluntary ethanol consumption in alcohol-preferring Alko alcohol (AA) rats by desoxypeganine and galanthamine. Eur J Pharmacol. 2005 Oct 17;522 (1-3) :72-7.