DR5 Polyclonal Antibody, AbBy Fluor™ 405 Conjugated
Product Specifications
Background
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis (By similarity) .
Synonyms
MK; DR5; Ly98; KILLER; TRICKB; TRAILR2; TRICK2A; TRICK2B; Tumor necrosis factor receptor superfamily member 10B; Death receptor 5; CD262; Tnfrsf10b
Gene ID
21933
Swiss Prot
Q9QZM4
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
301-381/381
Target
DR5
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 405
Source
KLH conjugated synthetic peptide derived from mouse DR5
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
401nm/421nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
21933
Predicted Cross Reactivity
Mouse, Rat
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15103622 1 Vial
Lentiviral mouse Cldn34d shRNA (UAS) - Lentiviral mouse Cldn34d shRNA (UAS, iRFP) (25)
Sign In for Pricing
View Details 
K4209008 1.0 µg DNA
Haus3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)
Sign In for Pricing
View Details 
K6369206 1.0 µg DNA
Tbc1d2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)
Sign In for Pricing
View Details