KHSRP Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity) . Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE) . May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Synonyms
Far upstream element-binding protein 2; KHSRP; FUSE-binding protein 2; KH type-splicing regulatory protein; KSRP; p75; FUBP2
Gene ID
8570
Swiss Prot
Q92945
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human
Immunogen
221-320/711
Target
KHSRP
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human KHSRP
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
8570
Predicted Cross Reactivity
Mouse, Rat, Dog, Pig, Horse
Curated Selection
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