DNA Ligase IV Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V (D) J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Synonyms
LIG4S; DNA ligase 4; DNA ligase IV; Polydeoxyribonucleotide synthase [ATP] 4; LIG4
Gene ID
3981
Swiss Prot
P49917
Host
Rabbit
Cross Reactivity
Human
Immunogen
51-150/911
Target
DNA Ligase IV
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human DNA Ligase IV
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
3981
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Sheep, Horse, Chicken, Rabbit
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
RC205904L4V 200 µL
TRF1 (TERF1) (NM_003218) Human Tagged ORF Clone Lentiviral Particle
Ask
View Details 
MBS6236225-01 0.1 mL
ZNF268 (Zinc Finger Protein 268, Zinc Finger Protein HZF3) (MaxLight 750)
Ask
View Details MBS6236225-02 5x 0.1 mL
ZNF268 (Zinc Finger Protein 268, Zinc Finger Protein HZF3) (MaxLight 750)
Ask
View Details