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KLHDC8B Polyclonal Antibody

Product Specifications

Background

Involved in pinching off the separated nuclei at the cleavage furrow and in cytokinesis (PubMed:20107318) . Required for mitotic integrity and maintenance of chromosomal stability. Protects cells against mitotic errors, centrosomal amplification, micronucleus formation and aneuploidy. Plays a key role of midbody function involving abscission of the daughter cells during cytokinesis and appropriate chromosomal and nuclear segregation into the daughter cells (PubMed:22988245, PubMed:23713010) .

Synonyms

FLJ11302; FP17659; Kelch domain containing 8B; Kelch domain containing protein 8B; Kelch domain-containing protein 8B; KLD8B_HUMAN; Klhdc8b; MGC35097; MGC94736.

Gene ID

200942

Swiss Prot

Q8IXV7

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Immunogen

201-300/354

Target

KLHDC8B

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human KLHDC8B

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-16762R

Gene ID URL

200942

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Sheep, Rabbit

Curated Selection

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