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Phospho-HEF1 (Ser369) Polyclonal Antibody, PE-Cy5 Conjugated

Product Specifications

Background

The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Synonyms

HEF1 (phospho S369) ; p-HEF1 (phospho S369) ; Cas like docking; Cas scaffolding protein family member 2; CAS-L; CAS2; CasL; CASL_HUMAN; CASS2; Crk associated substrate related; Crk associated substrate related protein; CRK-associated substrate-related protein; dJ49G10.2 (Enhancer of Filamentation 1 (HEF1) ) ; dJ49G10.2; dJ761I2.1 (enhancer of filamentation (HEF1) ) ; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF 1; HEF1

Gene ID

4739

Swiss Prot

Q14511

Modification Site

Ser369

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

HEF1

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy5

Source

KLH conjugated synthesised phosphopeptide derived from human HEF1 around the phosphorylation site of Ser369

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4739

Predicted Cross Reactivity

Cow, Sheep, Horse

Curated Selection

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