Phospho-HEF1 (Ser369) Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Synonyms
HEF1 (phospho S369) ; p-HEF1 (phospho S369) ; Cas like docking; Cas scaffolding protein family member 2; CAS-L; CAS2; CasL; CASL_HUMAN; CASS2; Crk associated substrate related; Crk associated substrate related protein; CRK-associated substrate-related protein; dJ49G10.2 (Enhancer of Filamentation 1 (HEF1) ) ; dJ49G10.2; dJ761I2.1 (enhancer of filamentation (HEF1) ) ; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF 1; HEF1
Gene ID
4739
Swiss Prot
Q14511
Modification Site
Ser369
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Target
HEF1
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthesised phosphopeptide derived from human HEF1 around the phosphorylation site of Ser369
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
4739
Predicted Cross Reactivity
Cow, Sheep, Horse
Curated Selection
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