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Phospho-HEF1 (Ser369) Polyclonal Antibody, APC Conjugated

Product Specifications

Background

The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Synonyms

HEF1 (phospho S369) ; p-HEF1 (phospho S369) ; Cas like docking; Cas scaffolding protein family member 2; CAS-L; CAS2; CasL; CASL_HUMAN; CASS2; Crk associated substrate related; Crk associated substrate related protein; CRK-associated substrate-related protein; dJ49G10.2 (Enhancer of Filamentation 1 (HEF1) ) ; dJ49G10.2; dJ761I2.1 (enhancer of filamentation (HEF1) ) ; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF 1; HEF1

Gene ID

4739

Swiss Prot

Q14511

Modification Site

Ser369

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

HEF1

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthesised phosphopeptide derived from human HEF1 around the phosphorylation site of Ser369

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4739

Predicted Cross Reactivity

Cow, Sheep, Horse

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