Phospho-HEF1 (Ser369) Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Synonyms
HEF1 (phospho S369) ; p-HEF1 (phospho S369) ; Cas like docking; Cas scaffolding protein family member 2; CAS-L; CAS2; CasL; CASL_HUMAN; CASS2; Crk associated substrate related; Crk associated substrate related protein; CRK-associated substrate-related protein; dJ49G10.2 (Enhancer of Filamentation 1 (HEF1) ) ; dJ49G10.2; dJ761I2.1 (enhancer of filamentation (HEF1) ) ; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF 1; HEF1
Gene ID
4739
Swiss Prot
Q14511
Modification Site
Ser369
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Target
HEF1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthesised phosphopeptide derived from human HEF1 around the phosphorylation site of Ser369
Applications
WB
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
4739
Predicted Cross Reactivity
Cow, Sheep, Horse
Curated Selection
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