Phospho-Erk1 (Thr202 + Tyr204) Polyclonal Antibody, Cy5 Conjugated
Product Specifications
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Synonyms
ERK/MAPKphospho T202/Y204; p44/42 MAP KinaseThr202; ERK 1; ERK; ERK-1; ERK1; Extracellular Signal Regulated Kinase 1; Extracellular signal related kinase 1; Extracellular signal-regulated kinase 1; HGNC6877; HS44KDAP; HUMKER1A; MAP kinase 1; MK03_RAT; MAP Kinase; MAP kinase isoform p44; MAPK 1; MAPK; MAPK1; MAPK3; MGC20180; Mitogen-activated protein kinase 1; OTTHUMP00000174538; OTTHUMP00000174541; p44 ERK1; p44 MAPK; p44-ERK1; p44-MAPK; P44ERK1; P44MAPK
Gene ID
5595
Modification Site
Thr202/Tyr204
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Phospho-Erk1 (Thr202 + Tyr204)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy5
Source
KLH conjugated synthetic phosphopeptide derived from human ERK1 around the phosphorylation site of Thr201/204
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
625,650nm/670nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5595
Predicted Cross Reactivity
Dog, Cow, Horse, Chicken, Rabbit, GuineaPig
Curated Selection
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