CD146 Polyclonal Antibody, RBITC Conjugated

Product Specifications

Background

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

Synonyms

CD146; MUC18; Cell surface glycoprotein MUC18; Cell surface glycoprotein P1H12; Melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; MCAM

Gene ID

4162

Swiss Prot

P43121

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

201-300/646

Target

CD146/MCAM

Clonality

Polyclonal

Isotype

IgG

Conjugation

RBITC

Source

KLH conjugated synthetic peptide derived from human CD146

Applications

WB, FCM

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4162

Predicted Cross Reactivity

Mouse, Dog, Cow, Horse

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

E2022Mo-01 48 Well

Mouse NACHT, LRR and PYD domains-containing protein 3, NLRP3 ELISA KIT

Ask

View Details

E2022Mo-02 96 Well

Mouse NACHT, LRR and PYD domains-containing protein 3, NLRP3 ELISA KIT

Ask

View Details

E2022Mo-03 5x 96 Tests

Mouse NACHT, LRR and PYD domains-containing protein 3, NLRP3 ELISA KIT

Ask

View Details

E2022Mo-04 10x 96 Tests

Mouse NACHT, LRR and PYD domains-containing protein 3, NLRP3 ELISA KIT

Ask

View Details

NBP2-89533F 0.1 mL

Rabbit Monoclonal Carboxypeptidase B1/CPB1 Antibody (329) [FITC]

Ask

View Details

TA303204 100 µg

LXN Goat Polyclonal Antibody

Ask

View Details