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Cathepsin K Polyclonal Antibody, PE-Cy5 Conjugated

Product Specifications

Background

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq, Jul 2008].

Synonyms

Cathepsin K; Procathepsin K; Cathepsin K precursor; Cathepsin O; Cathepsin O1; Cathepsin O2; Cathepsin X; CathepsinK; CTS02; CTSK; CTSK protein; CTSO; CTSO1; CTSO2; MGC23107; PKND; PYCD; Pycnodysostosis; cath-K; CK.

Gene ID

1513

Host

Rabbit

Cross Reactivity

Mouse, Rat

Target

Cathepsin K

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy5

Source

KLH conjugated synthetic peptide derived from human Capsin K

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

1µg/µl

Dilution

WB (WB=1:500-2000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1513

Curated Selection

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