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Phospho-ATP1A1 (Tyr260) Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+-ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta) . The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May2009].

Synonyms

Alpha 1 Sodium Potassium ATPase phospho Y260; Na, K-ATPase alpha-1; Na+/K+ ATPase 1; Sodium pump 1; ATP1A4; ATP1AL2; ATP1B; ATP1B1; ATPase Na+/K+ transporting alpha 1 polypeptide; ATPase Na+/K+ transporting alpha 4 polypeptide; ATPase Na+/K+ transporting beta 1 polypeptide; MGC1798; MGC25056; MGC3285; MGC51750; Sodium/potassium dependent ATPase beta 1 subunit; Sodium/potassium transporting ATPase alpha 1 chain; Sodium/potassium transporting ATPase subunit beta 1; alpha 1 Sodium Potassium ATPase.

Gene ID

476

Modification Site

Tyr260

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

Phospho-ATP1A1 (Tyr260)

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic phosphopeptide derived from human alpha 1 Sodium Potassium ATPase around the phosphorylation site of Tyr260

Applications

WB, ELISA, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

476

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Sheep, Pig, Horse

Curated Selection

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