IFI16 Polyclonal Antibody, Cy5 Conjugated
Product Specifications
Background
IFI16 is a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms
I16; Gamma interferon inducible protein 16; Gamma-interferon-inducible protein i16; IF16_HUMAN; i204; NGIP1; interferon activated gene 204; Interferon gamma induced protein I 16; Interferon gamma inducible protein 16; Interferon-inducible myeloid dferentiation transcriptional activator; p204; PYHIN2.
Gene ID
3428
Swiss Prot
Q16666
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
701-785/785
Target
I16
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy5
Source
KLH conjugated synthetic peptide derived from human IFI16
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
625,650nm/670nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3428
Predicted Cross Reactivity
Human
Curated Selection
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