Bcl-2 alpha Polyclonal Antibody
Product Specifications
Background
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) .
Synonyms
Bcl-2; PPP1R50; Apoptosis regulator Bcl-2; BCL2
Gene ID
596
Swiss Prot
P10415
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human
Immunogen
51-150/239
Target
Bcl-2 alpha
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human Bcl-2
Applications
WB, ELISA, FCM, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
596
Predicted Cross Reactivity
Dog, Cow, Sheep, Pig, Horse, Rabbit
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1483930 Inquire
Recombinant Nitrosomonas eutropha Peptide chain release factor 3 (prfC), partial
Sign In for Pricing
View Details 
TBI1562-5MG 5 mg
NSC47924, PHLP phosphatase inhibitor / Laminin inhibitor
Sign In for Pricing
View Details bs-9502R-Cy3 100 µL
Factor XI light chain Polyclonal Antibody, Cy3 Conjugated
Sign In for Pricing
View Details