Phospho-IFNAR1 (Tyr466) Polyclonal Antibody, PE Conjugated
Product Specifications
Background
IFNAR1 is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
Synonyms
Alpha type antiviral protein; AVP; Beta type antiviral protein; CRF2-1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; N alpha REC; N alpha REC; N alpha receptor; N alpha/beta Receptor alpha; N beta receptor; Interferon alpha/beta receptor 1; N-alpha/beta receptor 1; N-R-1; NAR; NAR1; NBR; RC; INAR1_HUMAN; Interferon alpha beta and omega receptor 1; Interferon alpha/beta receptor 1; Interferon alpha/beta receptor alpha chain; Interferon beta receptor 1; Type I interferon receptor 1.
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Target
Phospho-IFNAR1 (Tyr466)
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human IFNAR1 around the phosphorylation site of Tyr466
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Predicted Cross Reactivity
Human, Pig, Horse
Curated Selection
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