Phospho-IFNAR1 (Tyr466) Polyclonal Antibody, FITC Conjugated

Product Specifications

Background

IFNAR1 is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.

Synonyms

Alpha type antiviral protein; AVP; Beta type antiviral protein; CRF2-1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; N alpha REC; N alpha REC; N alpha receptor; N alpha/beta Receptor alpha; N beta receptor; Interferon alpha/beta receptor 1; N-alpha/beta receptor 1; N-R-1; NAR; NAR1; NBR; RC; INAR1_HUMAN; Interferon alpha beta and omega receptor 1; Interferon alpha/beta receptor 1; Interferon alpha/beta receptor alpha chain; Interferon beta receptor 1; Type I interferon receptor 1.

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Target

Phospho-IFNAR1 (Tyr466)

Clonality

Polyclonal

Isotype

IgG

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human IFNAR1 around the phosphorylation site of Tyr466

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Predicted Cross Reactivity

Human, Pig, Horse

Curated Selection

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