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IFITM5 Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

IFITM5 is a membrane protein thought to play a role in bone mineralization. This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195) .

Synonyms

Bone-restricted interferon-induced transmembrane protein-like protein; BRIL; Fragilis4; Hrmp1; ITM5; M5_HUMAN; Interferon-induced transmembrane protein 5.

Cellular Locus

Cell membrane

Host

Rabbit

Immunogen

1-100/132

Target

ITM5

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human IFITM5

Applications

WB, ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Predicted Cross Reactivity

Human

Curated Selection

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