IFITM5 Polyclonal Antibody, APC Conjugated

IFITM5 is a membrane protein thought to play a role in bone mineralization. This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195) .

Bone-restricted interferon-induced transmembrane protein-like protein; BRIL; Fragilis4; Hrmp1; ITM5; M5_HUMAN; Interferon-induced transmembrane protein 5.