BPU
BPU arrests cell cycle progression in the sub-G1 phase. BPU is an anticancer agent through inhibiting blood vessel formation in tumor tissues[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; MMP
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bpu.html
Purity
99.04
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(N)N(C1=NC=C(Br)N=C1)CC2=CC=CC(C(F)(F)F)=C2
Molecular Formula
C13H10BrF3N4O
Molecular Weight
375.14
References & Citations
[1]Yasser Hussein Issa Mohammed, et al. Discovery of 1- (5-bromopyrazin-2-yl) -1-[3- (trifluoromethyl) benzyl]urea as a promising anticancer drug via synthesis, characterization, biological screening, and computational studies. Sci Rep. 2023, 13, 1.|[2]Yasser Hussein Issa Mohammed, et al. Discovery of 1- (5-bromopyrazin-2-yl) -1-[3- (trifluoromethyl) benzyl]urea as a promising anticancer drug via synthesis, characterization, biological screening, and computational studies. Scientific Reports. Dec 12.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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