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HERC4 Polyclonal Antibody, PE Conjugated

Product Specifications

Background

HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710) -like domain (RLD) . The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]) .

Synonyms

DKFZP564G092; HECT and RLD domain containing E3 ubiquitin protein ligase 4; HECT domain and RCC1 like domain containing protein 4; HECT domain and RCC1-like domain-containing protein 4; Hect domain and RLD 4; HERC 4; HERC4; HERC4_HUMAN; KIAA1593; Probable E3 ubiquitin protein ligase HERC4; Probable E3 ubiquitin-protein ligase HERC4.

Gene ID

26091

Cellular Locus

Cytoplasm

Host

Rabbit

Immunogen

301-400/1057

Target

HERC4

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE

Source

KLH conjugated synthetic peptide derived from human HERC4

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

26091

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse

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