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Folinic acid (calcium) (Standard)

Selected Variant

HY-13664R-01

Size: 10 mg

Folinic acid (calcium) (Standard) is the analytical standard of Folinic acid (calcium) . This product is intended for research and analytical applications. Folinic acid calcium (Leucovorin calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity[1].

Product Specifications

CAS Number

1492-18-8

Product Name Alternative

Leucovorin (calcium) (Standard) ; Calcium folinate (Standard)

UNSPSC

12352005

Target

Antifolate; Endogenous Metabolite; Reference Standards

Type

Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/folinic-acid-calcium-standard.html

Smiles

O=C(N[C@H](C([O-])=O)CCC([O-])=O)C(C=C1)=CC=C1NCC(N2C=O)CNC3=C2C(N=C(N)N3)=O.[Ca+2]

Molecular Formula

C20H21CaN7O7

Molecular Weight

511.50

References & Citations

[1]Keshava C, et al. Inhibition of methotrexate-induced chromosomal damage by folinic acid in V79 cells. Mutat Res. 1998 Feb 2;397 (2) :221-8.|[2]Iqbal MP, et al. Effect of methotrexate and folinic acid on skeletal growth in mice. Acta Paediatr. 2003 Dec;92 (12) :1438-44.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

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