Phospho-ERK1 + 2 (Thr183/Tyr185) Polyclonal Antibody, Cy7 Conjugated
Product Specifications
Background
Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity (By similarity) .
Synonyms
ERK; Erk2; MAPK2; PRKM2; Prkm1; C78273; p41mapk; p42mapk; AA47128; AU18647; 93612K14Rik; Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2; Mapk1; Mapk
Gene ID
26413
Swiss Prot
P63085
Modification Site
Thr183/Tyr 185
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-ERK1 + 2 (Thr183/Tyr185)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy7
Source
KLH conjugated synthetic phosphopeptide derived from mouse ERK2 around the phosphorylation site of Thr183 and Tyr 185
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
743nm/767nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
26413
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Horse, Chicken, Rabbit, GuineaPig
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7204824-01 48 Well
Human Alpha 1, 3 mannosyl glycoprotein 4 beta N acetylglucosaminyltransferase B (MGAT4B) ELISA Kit
Ask
View Details 
MBS7204824-02 96 Well
Human Alpha 1, 3 mannosyl glycoprotein 4 beta N acetylglucosaminyltransferase B (MGAT4B) ELISA Kit
Ask
View Details 
MBS7204824-03 5x 96 Well
Human Alpha 1, 3 mannosyl glycoprotein 4 beta N acetylglucosaminyltransferase B (MGAT4B) ELISA Kit
Ask
View Details MBS7204824-04 10x 96 Well
Human Alpha 1, 3 mannosyl glycoprotein 4 beta N acetylglucosaminyltransferase B (MGAT4B) ELISA Kit
Ask
View Details 