E cadherin Polyclonal Antibody, PE-Cy5 Conjugated
Product Specifications
Background
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
Synonyms
UVO; CDHE; ECAD; LCAM; Arc-1; CD324; Cadherin-1; CAM 12/8; Epithelial cadherin; E-cadherin; Uvomorulin; CDH1
Gene ID
999
Swiss Prot
P12830
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
841-882/882
Target
E cadherin
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE-Cy5
Source
KLH conjugated synthetic peptide derived from human E-cadherin
Applications
WB, FCM
Purification
Purified by Protein A.
Excitation Emission
488nm/670nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
999
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Pig, Horse, Chicken
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
